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In 1939, the Council of Pharmacy and Chemistry of the American Medical Association refused to accept testosterone for New and Nonofficial Remedies stating, ‘the involutional melancholia of males, for which testosterone has been suggested, has not been subjected to adequate trials, to justify androgenic therapy other than on an experimental basis. Barahal (1940) also found little or no change in the mental condition of 7 psychotic male homosexual patients who were treated with intramuscular injection of testosterone propionate (25mg) 3 times weekly for 18 months. In addition, Pardoll and Belinson (1941) reported that mental improvement was not sufficiently pronounced to warrant administering testosterone propionate as routine treatment for the male involutional psychoses after treating 11 males with 10mg doses of testosterone propionate twice weekly for 3 months and observing behaviour for 2 months following cessation of therapy, bulking up calories. Is crazybulk real steroids
This is partially related to the negative effect of testosterone on the lipid profile and HDL levels , . Other large cohort studies also confirm the increased risk of heart attacks and stroke due to TRT . Testosterone can also increase the growth of cancer in patients with prostate carcinoma .
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